ID   SfSWT-7
AC   CVCL_C3MG
DR   Wikidata; Q116050498
RX   Patent=US9045778;
RX   PubMed=23848607;
CC   Group: Insect cell line.
CC   Group: Patented cell line.
CC   Group: Recombinant protein production insect cell line.
CC   Characteristics: Can produce sulfated complex N-glycans. The expression of the carbohydrate modidying enzymes is under the transcriptional control of baculovirus immediate early 1 (ie1) promoter and homologous region 5 (hr5) enhancer elements.
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7045; MGAT2.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:1891160; Chst2.
CC   Genetic integration: Method=Transfection; Gene=MGI; MGI:2685834; Gal3st2.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=VGNC; VGNC:26388; Bovine B4GALT1.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
OX   NCBI_TaxID=7108; ! Spodoptera frugiperda (Fall armyworm)
HI   CVCL_4U10 ! Sf900+
SX   Female
AG   Pupal stage
CA   Spontaneously immortalized cell line
DT   Created: 15-12-22; Last updated: 10-04-25; Version: 7
//
RX   Patent=US9045778;
RA   Jarvis D.L.;
RT   "An insect cell line for production of recombinant glycoproteins with
RT   sulfated complex N-glycans.";
RL   Patent number US9045778, 02-Jun-2015.
//
RX   PubMed=23848607; DOI=10.1021/pr400329k; PMCID=PMC3800089;
RA   An Y.-M., Rininger J.A., Jarvis D.L., Jing X.-H., Ye Z.-P., Aumiller J.J.,
RA   Eichelberger M.C., Cipollo J.F.;
RT   "Comparative glycomics analysis of influenza Hemagglutinin (H5N1)
RT   produced in vaccine relevant cell platforms.";
RL   J. Proteome Res. 12:3707-3720(2013).
//