ID   MSHRIe002-A-SOX17 overexpressing 1
AC   CVCL_C3L8
SY   CA2 Cre Sox17D
DR   GEO; GSM272918
DR   Wikidata; Q114312323
RX   PubMed=18682240;
CC   Characteristics: Using Cre the loxP-BetaGeo(lacZ-neo)-polyA-loxP section of the parent control cell line construct was excised leaving the SOX17-IRES-PuroR-polyA part. This cell line overexpresses SOX17 and can be selected via puromycin resistance (PubMed=18682240).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:18122; SOX17.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C3L6 ! MSHRIe002-A-SOX17 control 1
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 22-09-22; Last updated: 10-04-25; Version: 7
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RX   PubMed=18682240; DOI=10.1016/j.stem.2008.06.018;
RA   Seguin C.A., Draper J.S., Nagy A., Rossant J.;
RT   "Establishment of endoderm progenitors by SOX transcription factor
RT   expression in human embryonic stem cells.";
RL   Cell Stem Cell 3:182-195(2008).
//