ID   U-251MG-GFP
AC   CVCL_C3I5
SY   U251-control
DR   cancercelllines; CVCL_C3I5
DR   GEO; GSM1517803
DR   GEO; GSM1517804
DR   GEO; GSM1517805
DR   Wikidata; Q114313139
RX   PubMed=25877876;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu242Valfs*15 (c.723_724dupTG); ClinVar=VCV000536553; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Brain, parietal lobe; UBERON=UBERON_0001872.
DI   NCIt; C60781; Astrocytoma
DI   ORDO; Orphanet_94; Astrocytoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0021 ! U-251MG
SX   Male
AG   75Y
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 10-04-25; Version: 8
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RX   PubMed=25877876; DOI=10.1158/0008-5472.CAN-14-1433; PMCID=PMC4417379;
RA   Lin D.-C., Xu L., Chen Y., Yan H.-Y., Hazawa M., Doan N.B., Said J.W.,
RA   Ding L.-W., Liu L.-Z., Yang H.H., Yu S.-Z., Kahn M., Yin D.,
RA   Koeffler H.P.;
RT   "Genomic and functional analysis of the E3 ligase PARK2 in glioma.";
RL   Cancer Res. 75:1815-1827(2015).
//