ID   RCC-26/CD80
AC   CVCL_C3HQ
SY   RCC-26/B7.1
DR   Wikidata; Q114312774
RX   PubMed=11175312;
RX   PubMed=15755994;
RX   PubMed=15997395;
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:1700; CD80.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
CC   Cell type: Epithelial cell of kidney; CL=CL_0002518.
DI   NCIt; C4033; Clear cell renal cell carcinoma
DI   ORDO; Orphanet_319276; Clear cell renal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_VQ70 ! RCC-26
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 7
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RX   PubMed=11175312; DOI=10.1038/sj.gt.3301349;
RA   Schendel D.J., Frankenberger B., Jantzer P., Cayeux S., Noessner E.,
RA   Willimsky G., Maget B., Pohla H., Blankenstein T.;
RT   "Expression of B7.1 (CD80) in a renal cell carcinoma line allows
RT   expansion of tumor-associated cytotoxic T lymphocytes in the presence
RT   of an alloresponse.";
RL   Gene Ther. 7:2007-2014(2000).
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RX   PubMed=15755994; DOI=10.1158/1078-0432.CCR-04-1883;
RA   Frankenberger B., Pohla H., Noessner E., Willimsky G., Papier B.,
RA   Pezzutto A., Kopp J., Oberneder R., Blankenstein T., Schendel D.J.;
RT   "Influence of CD80, interleukin-2, and interleukin-7 expression in
RT   human renal cell carcinoma on the expansion, function, and survival of
RT   tumor-specific CTLs.";
RL   Clin. Cancer Res. 11:1733-1742(2005).
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RX   PubMed=15997395; DOI=10.1007/s00345-005-0505-5;
RA   Frankenberger B., Regn S., Geiger C., Noessner E., Falk C.S.,
RA   Pohla H., Javorovic M., Silberzahn T., Wilde S., Buchner A.,
RA   Siebels M., Oberneder R., Willimsky G., Pezzutto A., Blankenstein T.,
RA   Schendel D.J.;
RT   "Cell-based vaccines for renal cell carcinoma: genetically-engineered
RT   tumor cells and monocyte-derived dendritic cells.";
RL   World J. Urol. 23:166-174(2005).
//