ID   TYR1-hiPSC1
AC   CVCL_C361
SY   TYR.1.H.iPSC.1; TYR1hiPSC1; T-hiPSC1; RIi005-A
DR   hPSCreg; RIi005-A
DR   ISCR; 1411
DR   RSCB; RSCB0067
DR   SKIP; SKIP002400
DR   SKIP; SKIP005840
DR   Wikidata; Q54973479
RX   PubMed=20821352;
RX   PubMed=22543856;
CC   From: Royan Institute; Theran; Iran.
CC   Population: Iranian.
CC   Sequence variation: Mutation; HGNC; 3579; FAH; Simple; p.Gln64His (c.192G>T); ClinVar=VCV000021054; Zygosity=Unspecified (PubMed=20821352).
CC   Omics: Proteome analysis by 2D-DE/MS.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C98641; Tyrosinemia type I
DI   ORDO; Orphanet_882; Tyrosinemia type 1
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C362 ! TYR1-hiPSC2
OI   CVCL_C363 ! TYR1-hiPSC3
OI   CVCL_C364 ! TYR1-hiPSC4
OI   CVCL_C365 ! TYR1-hiPSC5
OI   CVCL_C366 ! TYR1-hiPSC6
OI   CVCL_C367 ! TYR1-hiPSC7
SX   Female
AG   6Y
CA   Induced pluripotent stem cell
DT   Created: 22-10-12; Last updated: 29-06-23; Version: 16
//
RX   PubMed=20821352; DOI=10.1007/s12015-010-9189-3;
RA   Ghodsizadeh A., Taei A., Totonchi M., Seifinejad A., Gourabi H.,
RA   Pournasr B., Aghdami N., Malekzadeh R., Almadani N., Salekdeh G.H.,
RA   Baharvand H.;
RT   "Generation of liver disease-specific induced pluripotent stem cells
RT   along with efficient differentiation to functional hepatocyte-like
RT   cells.";
RL   Stem Cell Rev. Rep. 6:622-632(2010).
//
RX   PubMed=22543856; DOI=10.1039/c2mb25018g;
RA   Faradonbeh M.Z., Gharechahi J., Mollamohammadi S., Pakzad M., Taei A.,
RA   Rassouli H., Baharvand H., Salekdeh G.H.;
RT   "An orthogonal comparison of the proteome of human embryonic stem
RT   cells with that of human induced pluripotent stem cells of different
RT   genetic background.";
RL   Mol. Biosyst. 8:1833-1840(2012).
//