ID   STBCi322-A-1
AC   CVCL_C1XW
SY   NKX6.1-GFP reporter line; NKX6.1-GFP clone 1a-10-3; AZi323-A-1
DR   hPSCreg; STBCi322-A-1
DR   Wikidata; Q114313049
RX   PubMed=29734117;
CC   From: AstraZeneca; Cambridge; United Kingdom.
CC   Characteristics: Using CRISPR/Cas9 a T2A-GFP-LoxP-PGK-Neo-LoxP construct was introduced at the C-terminus of NKX6-1. Subsequently the LoxP-PGK-Neo-LoxP sequence was removed by Cre-mediated excision (PubMed=29734117).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_ZX55 ! STBCi322-A
SX   Female
AG   36Y
CA   Induced pluripotent stem cell
DT   Created: 22-09-22; Last updated: 29-06-23; Version: 4
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RX   PubMed=29734117; DOI=10.1016/j.scr.2018.04.010;
RA   Gupta S.K., Wesolowska-Andersen A., Ringgaard A.K., Jaiswal H.,
RA   Song L.-Y., Hastoy B., Ingvorsen C., Taheri-Ghahfarokhi A., Magnusson B.,
RA   Maresca M., Jensen R.R., Beer N.L., Fels J.J., Grunnet L.G.,
RA   Thomas M.K., Gloyn A.L., Hicks R., McCarthy M.I., Hansson M.,
RA   Honore C.;
RT   "NKX6.1 induced pluripotent stem cell reporter lines for isolation and
RT   analysis of functionally relevant neuronal and pancreas populations.";
RL   Stem Cell Res. 29:220-231(2018).
//