ID   TT10902
AC   CVCL_C1MP
DR   cancercelllines; CVCL_C1MP
DR   Wikidata; Q114313134
RX   PubMed=29100338;
CC   Population: Chinese.
CC   Doubling time: 54.9 +- 0.1 hours (PubMed=29100338).
CC   Sequence variation: Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Lys28Met (c.83A>T) (H3.3K27M); ClinVar=VCV000376435; Zygosity=Unspecified (PubMed=29100338).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=29100338).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273Cys (c.817C>T); ClinVar=VCV000043594; Zygosity=Unspecified (PubMed=29100338).
CC   Derived from site: In situ; Brainstem, pons; UBERON=UBERON_0000988.
DI   NCIt; C94764; Diffuse intrinsic pontine glioma
DI   ORDO; Orphanet_497188; Diffuse intrinsic pontine glioma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   8Y
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=29100338; DOI=10.18632/oncotarget.19656; PMCID=PMC5652732;
RA   Xu C., Liu X.-Q., Geng Y.-B., Bai Q.-R., Pan C.-C., Sun Y., Chen X.,
RA   Yu H., Wu Y.-L., Zhang P., Wu W.-H., Wang Y., Wu Z., Zhang J.-T.,
RA   Wang Z.-H., Yang R., Lewis J., Bigner D.D., Zhao F.-P., He Y.-P., Yan H.,
RA   Shen Q., Zhang L.-W.;
RT   "Patient-derived DIPG cells preserve stem-like characteristics and
RT   generate orthotopic tumors.";
RL   Oncotarget 8:76644-76655(2017).
//