ID   HT-29 Y1-16
AC   CVCL_C1KN
SY   Y1-16
DR   cancercelllines; CVCL_C1KN
DR   Wikidata; Q114311667
RX   CelloPub=CLPUB00715;
RX   PubMed=8886416;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=RGD; 3198; Npy1r.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4349; Colon adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0320 ! HT-29
SX   Female
AG   44Y
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 7
//
RX   CelloPub=CLPUB00715;
RA   Holliday N.D.;
RT   "Functional expression of native and mutant Y1 receptors in stably
RT   transfected adenocarcinoma cell lines.";
RL   Thesis PhD (1998); University College London; London; United Kingdom.
//
RX   PubMed=8886416; DOI=10.1111/j.1476-5381.1996.tb15989.x; PMCID=PMC1915860;
RA   Holliday N.D., Cox H.M.;
RT   "The functional investigation of a human adenocarcinoma cell line,
RT   stably transfected with the neuropeptide Y Y1 receptor.";
RL   Br. J. Pharmacol. 119:321-329(1996).
//