ID   AT1BR44neo
AC   CVCL_C1HN
SY   AT1BR44 neo
DR   Wikidata; Q114310633
RX   CelloPub=CLPUB00712;
RX   PubMed=9357546;
RX   PubMed=19935656;
CC   Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (CelloPub=CLPUB00712; PubMed=19935656).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
DI   NCIt; C2887; Ataxia telangiectasia syndrome
DI   ORDO; Orphanet_100; Ataxia telangiectasia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_WX69 ! AT1BR
SX   Male
AG   7Y
CA   Transformed cell line
DT   Created: 22-09-22; Last updated: 10-09-24; Version: 5
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RX   CelloPub=CLPUB00712;
RA   Henson J.D.;
RT   "The role of alternative lengthening of telomeres in human cancer.";
RL   Thesis PhD (2006); University of Sydney; Sydney; Australia.
//
RX   PubMed=9357546; DOI=10.1016/S0027-5107(97)00119-x;
RA   Sprung C.N., Bryan T.M., Reddel R.R., Murnane J.P.;
RT   "Normal telomere maintenance in immortal ataxia telangiectasia cell
RT   lines.";
RL   Mutat. Res. 379:177-184(1997).
//
RX   PubMed=19935656; DOI=10.1038/nbt.1587;
RA   Henson J.D., Cao Y., Huschtscha L.I., Chang A.C.-M., Au A.Y.M.,
RA   Pickett H.A., Reddel R.R.;
RT   "DNA C-circles are specific and quantifiable markers of
RT   alternative-lengthening-of-telomeres activity.";
RL   Nat. Biotechnol. 27:1181-1185(2009).
//