DR   Wikidata; Q114312845
RX   PubMed=35692635;
CC   Characteristics: Control cell line for the cancer pathway knockout panel.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 7413; MTAP.
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: In situ; Eye, retina, retinal pigment epithelium; UBERON=UBERON_0001782.
CC   Cell type: Retinal pigment epithelial cell; CL=CL_0002586.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_4388 ! hTERT-RPE1
SX   Female
AG   1Y
CA   Telomerase immortalized cell line
DT   Created: 22-09-22; Last updated: 05-10-23; Version: 5
RX   PubMed=35692635; DOI=10.1016/j.isci.2022.104437;
RA   Cook A.L., Wyhs N., Sur S., Ptak B., Popoli M., Dobbyn L.,
RA   Papadopoulos T., Bettegowda C., Papadopoulos N., Vogelstein B.,
RA   Zhou S.-B., Kinzler K.W.;
RT   "An isogenic cell line panel for sequence-based screening of targeted
RT   anticancer drugs.";
RL   IScience 25:104437.1-104437.14(2022).