ID   RPTEC_APC_488
AC   CVCL_C1BM
DR   Wikidata; Q114312886
RX   PubMed=35692635;
CC   Part of: Cancer Pathway Knockout Panel.
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:583; APC.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
CC   Cell type: Epithelial cell of proximal tubule; CL=CL_0002306.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_K278 ! RPTEC/TERT1
SX   Male
AG   Adult
CA   Telomerase immortalized cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=35692635; DOI=10.1016/j.isci.2022.104437; PMCID=PMC9184558;
RA   Cook A.L., Wyhs N., Sur S., Ptak B., Popoli M., Dobbyn L.,
RA   Papadopoulos T., Bettegowda C., Papadopoulos N., Vogelstein B.,
RA   Zhou S.-B., Kinzler K.W.;
RT   "An isogenic cell line panel for sequence-based screening of targeted
RT   anticancer drugs.";
RL   iScience 25:104437.1-104437.13(2022).
//