ID   BL-64
AC   CVCL_C155
SY   BL64; BL 64; IARC/BL64; IARC/BL 64; IARC-BL64; IARC BL64; IARC BL 64
DR   Cosmic; 2361384
DR   DSMZ; ACC-919
DR   DSMZCellDive; ACC-919
DR   Wikidata; Q54797235
RX   PubMed=2470097;
RX   PubMed=3458667;
RX   PubMed=3905596;
RX   PubMed=3934070;
RX   PubMed=6090749;
RX   PubMed=6592381;
RX   PubMed=8547074;
RX   PubMed=10997876;
RX   PubMed=22120970;
CC   From: International Agency of Research on Cancer (IARC); Lyon; France.
CC   Population: Africans north of the Sahara.
CC   Doubling time: ~30-50 hours (DSMZ=ACC-919).
CC   Sequence variation: Gene fusion; HGNC; 5715; IGK + HGNC; 7553; MYC; Name(s)=MYC-IGK (PubMed=3458667; PubMed=22120970).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): DSMZ=ACC-919
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12
ST   D16S539: 9,11
ST   D18S51: 13,17
ST   D19S433: 12,15
ST   D21S11: 29,32.2
ST   D2S1338: 18,24
ST   D3S1358: 16,17
ST   D5S818: 12,13
ST   D7S820: 9,11
ST   D8S1179: 11,12
ST   FGA: 24
ST   Penta D: 10,14
ST   Penta E: 10,11
ST   TH01: 6,9
ST   TPOX: 8,9
ST   vWA: 16,17
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_M556 ! BL-61
OI   CVCL_IV10 ! IARC-549
SX   Male
AG   4Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-09-24; Version: 23
//
RX   PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109;
RA   Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.;
RT   "Identification of a human transcription unit affected by the variant
RT   chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989).
//
RX   PubMed=3458667; DOI=10.1007/BF00292668;
RA   Hameister H., Adolph S.;
RT   "In situ hybridization studies on variant t(2;8) translocations in
RT   Burkitt lymphoma lines.";
RL   Hum. Genet. 73:73-76(1986).
//
RX   PubMed=3905596;
RA   Favrot M.-C., Philip I., Philip T., Cabrillat H., Pinatel C.,
RA   Dore J.-F., Lenoir G.M.;
RT   "Immunophenotypic classification of 28 Burkitt cell lines with
RT   monoclonal antibodies and reagent selection for bone-marrow purging.";
RL   IARC Sci. Publ. 60:447-452(1985).
//
RX   PubMed=3934070;
RA   Lenoir G.M., Vuillaume M., Bonnardel C.;
RT   "The use of lymphomatous and lymphoblastoid cell lines in the study of
RT   Burkitt's lymphoma.";
RL   IARC Sci. Publ. 60:309-318(1985).
//
RX   PubMed=6090749; DOI=10.1093/jnci/73.4.835;
RA   Philip I., Philip T., Favrot M.-C., Vuillaume M., Fontaniere B.,
RA   Chamard D., Lenoir G.M.;
RT   "Establishment of lymphomatous cell lines from bone marrow samples
RT   from patients with Burkitt's lymphoma.";
RL   J. Natl. Cancer Inst. 73:835-840(1984).
//
RX   PubMed=6592381; DOI=10.1093/jnci/73.4.841;
RA   Favrot M.-C., Philip I., Philip T., Portoukalian J., Dore J.-F.,
RA   Lenoir G.M.;
RT   "Distinct reactivity of Burkitt's lymphoma cell lines with eight
RT   monoclonal antibodies correlated with the ethnic origin.";
RL   J. Natl. Cancer Inst. 73:841-847(1984).
//
RX   PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x;
RA   Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G.,
RA   Uppenkamp M.J., Nowrousian M.R., Seeber S., Opalka B.;
RT   "Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and
RT   lymphoblastic leukaemia cell lines.";
RL   Br. J. Haematol. 91:350-354(1995).
//
RX   PubMed=10997876; DOI=10.1093/dnares/7.4.261;
RA   Hauptschein R.S., Gaidano G., Rao P.H., Scotto L., Edwards Y.H.,
RA   Chaganti R.S.K., Dalla-Favera R.;
RT   "An apparent interlocus gene conversion-like event at a putative tumor
RT   suppressor gene locus on human chromosome 6q27 in a Burkitt's
RT   lymphoma cell line.";
RL   DNA Res. 7:261-272(2000).
//
RX   PubMed=22120970; DOI=10.1002/gcc.21915;
RA   Kroenlein H., Schwartz S., Reinhardt R., Rieder H., Molkentin M.,
RA   Gokbuget N., Hoelzer D., Thiel E., Burmeister T.;
RT   "Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade
RT   lymphoma/leukemia by long-distance inverse PCR.";
RL   Genes Chromosomes Cancer 51:290-299(2012).
//