ID   SSK41
AC   CVCL_C123
SY   SSK-41
DR   cancercelllines; CVCL_C123
DR   Cosmic; 1291154
DR   Cosmic; 2297033
DR   Cosmic; 2590021
DR   GEO; GSM115988
DR   GEO; GSM866166
DR   GEO; GSM1035347
DR   GEO; GSM1035348
DR   Progenetix; CVCL_C123
DR   Wikidata; Q54955698
RX   PubMed=1712020;
RX   PubMed=2518730;
RX   PubMed=7849311;
RX   PubMed=16960149;
CC   Characteristics: Expresses surface IgM but can spontaneously switch to the production of IgG1 or IgG3.
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Variations; Array-based CGH.
CC   Miscellaneous: Originally assigned to be from a follicular lymphoma.
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4663; Splenic marginal zone lymphoma
DI   ORDO; Orphanet_86854; Splenic marginal zone lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 16
//
RX   PubMed=1712020; DOI=10.1016/S0021-9258(18)98929-5;
RA   Mizuta T.-R., Suzuki N., Shimizu A., Honjo T.;
RT   "Duplicated variable region genes account for double isotype
RT   expression in a human leukemic B-cell line that gives rise to single
RT   isotype-expressing cells.";
RL   J. Biol. Chem. 266:12514-12521(1991).
//
RX   PubMed=2518730; DOI=10.1093/intimm/1.6.631;
RA   Sideras P., Mizuta T.-R., Kanamori H., Suzuki N., Okamoto M., Kuze K.,
RA   Ohno H., Doi S., Fukuhara S., Hassan M.S., Hammarstrom L., Smith E.,
RA   Shimizu A., Honjo T.;
RT   "Production of sterile transcripts of C gamma genes in an
RT   IgM-producing human neoplastic B cell line that switches to
RT   IgG-producing cells.";
RL   Int. Immunol. 1:631-642(1989).
//
RX   PubMed=7849311; DOI=10.1182/blood.V85.4.893.bloodjournal854893;
RA   Stranks G., Height S.E., Mitchell P., Jadayel D.M., Yuille M.A.R.,
RA   De Lord C.F.M., Clutterbuck R.D., Treleaven J.G., Powles R.L.,
RA   Nacheva E., Oscier D.G., Karpas A., Lenoir G.M., Smith S.D.,
RA   Millar J.L., Catovsky D., Dyer M.J.S.;
RT   "Deletions and rearrangement of CDKN2 in lymphoid malignancy.";
RL   Blood 85:893-901(1995).
//
RX   PubMed=16960149; DOI=10.1182/blood-2006-06-026500;
RA   Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R.,
RA   Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M.,
RA   Rosenwald A., Sugimoto K.-j., Wheat L.M., Karran E.L., Garcia J.F.,
RA   Sanchez-Verde L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S.,
RA   Martinez-Climent J.A.;
RT   "Homozygous deletions localize novel tumor suppressor genes in B-cell
RT   lymphomas.";
RL   Blood 109:271-280(2007).
//