ID   BNI-VS-50
AC   CVCL_C0X3
DR   cancercelllines; CVCL_C0X3
DR   GEO; GSM5460962
DR   Wikidata; Q114310760
RX   PubMed=35394061;
CC   Population: Chinese.
CC   Characteristics: Established from the PDX-NF2-VS-02 xenograft.
CC   Sequence variation: Mutation; HGNC; HGNC:7773; NF2; Simple; p.Arg57Ter (c.169C>T); ClinVar=VCV000003285; Zygosity=Unspecified (PubMed=35394061).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
CC   Cell type: Schwann cell; CL=CL_0002573.
ST   Source(s): PubMed=35394061
ST   Amelogenin: X,Y
ST   CSF1PO: 10,13
ST   D12S391: 18,20
ST   D13S317: 8,12
ST   D16S539: 9,11
ST   D18S51: 13,19
ST   D19S433: 13,14
ST   D1S1656: 15,16
ST   D21S11: 30
ST   D2S1338: 18,24
ST   D3S1358: 15,16
ST   D5S818: 10,13
ST   D6S1043: 18,19
ST   D7S820: 10,11
ST   D8S1179: 10,12
ST   FGA: 23
ST   Penta D: 11,13
ST   Penta E: 11,19
ST   TH01: 7,9
ST   TPOX: 8,9
ST   vWA: 15,18
DI   NCIt; C3274; Neurofibromatosis type 2
DI   NCIt; C3276; Vestibular schwannoma
DI   ORDO; Orphanet_637; Neurofibromatosis type 2
DI   ORDO; Orphanet_252175; Vestibular schwannoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   38Y
CA   Cancer cell line
DT   Created: 22-09-22; Last updated: 10-04-25; Version: 7
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RX   PubMed=35394061; DOI=10.1002/path.5908;
RA   Zhao F., Chen Y., Li S.-W., Zhang J., Zhang S., Zhao X.-B., Yang Z.-J.,
RA   Wang B., He Q.-Y., Wang L.-M., Xu L., Liu P.-N.;
RT   "Novel patient-derived xenograft and cell line models for therapeutic
RT   screening in NF2-associated schwannoma.";
RL   J. Pathol. 257:620-634(2022).
//