ID   HT22 TR/TO-rKlf9 clone 2.1
AC   CVCL_C0UA
SY   HT22 [TR/TO-rKlf9] clone 2.1; HT-22 [TR/TO-rKlf9] clone 2.1; HT22 [TR/TO-Klf9] line 2-1; HT22[TR/TO-Klf9]
DR   Kerafast; EMU045
DR   Wikidata; Q112929760
RX   PubMed=28407733;
RX   PubMed=32241200;
CC   Characteristics: Doxycycline induced expression of Klf9. Transfected with both pCDNA4:TO-Klf9 containing CMV-tetO2-Klf9 and the zeocin resistance gene (ble) and pCDNA6:TR containing tetR and the blasticidin resistance gene Bsr.
CC   Genetic integration: Method=Transfection; Gene=RGD; 70934; Klf9.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P33967; B.cereus Bsr.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Brain, hippocampus; UBERON=UBERON_0002421.
CC   Cell type: Neuron; CL=CL_0000540.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0321 ! HT22
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 10-04-25; Version: 8
//
RX   PubMed=28407733; DOI=10.1186/s12864-017-3640-7; PMCID=PMC5390390;
RA   Knoedler J.R., Subramani A., Denver R.J.;
RT   "The Kruppel-like factor 9 cistrome in mouse hippocampal neurons
RT   reveals predominant transcriptional repression via proximal promoter
RT   binding.";
RL   BMC Genomics 18:299.1-299.22(2017).
//
RX   PubMed=32241200; DOI=10.1177/0748730420913205; PMCID=PMC9199006;
RA   Knoedler J.R., Avila-Mendoza J., Subramani A., Denver R.J.;
RT   "The paralogous Kruppel-like factors 9 and 13 regulate the mammalian
RT   cellular circadian clock output gene Dbp.";
RL   J. Biol. Rhythms 35:257-274(2020).
//