ID   ACTOne cAMP-PDE4C
AC   CVCL_C0U4
SY   ACTOne PDE4C; PDE4C ACTOne; CHO-K1-CNG-PDE4C
DR   Wikidata; Q112929140
CC   Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
CC   Characteristics: Expresses a constitutively active over-expressed Gs-coupled GPCR.
CC   Transfected with: RGD; 2367; Cnga2 (with p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
CC   Transfected with: HGNC; 8782; PDE4C.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transfected with: UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR).
CC   Discontinued: Codex Biosolutions; Catalog number CL-02-PDE4C.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_C0RV ! CHO-K1-CNG-Gs
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 23-06-22; Last updated: 30-01-24; Version: 5
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