ID   ACTOne CB1
AC   CVCL_C0SB
SY   ACTOne HEK-CNG+CB1; HEK-CNG + CB1
DR   Wikidata; Q112929142
RX   PubMed=26772161;
RX   PubMed=27115025;
WW   http://www.codexbiosolutions.com/wp-content/uploads/cb-80300-205.pdf
CC   Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Codex BioSolutions).
CC   Transfected with: RGD; 2367; Cnga2 (with p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
CC   Transfected with: HGNC; 2159; CNR1.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C0RU ! HEK293-CNG
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 29-06-23; Version: 4
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RX   PubMed=26772161; DOI=10.1016/j.ab.2015.12.019;
RA   Presley C.S., Abidi A.H., Moore B.M. II;
RT   "Cannabinoid receptor 1 ligands revisited: pharmacological assessment
RT   in the ACTOne system.";
RL   Anal. Biochem. 498:8-28(2016).
//
RX   PubMed=27115025; DOI=10.1016/j.dib.2016.03.086;
RA   Presley C.S., Abidi A.H., Moore B.M. II;
RT   "Optimization of cAMP fluorescence dataset from ACTOne cannabinoid
RT   receptor 1 cell line.";
RL   Data Brief 7:1118-1123(2016).
//