ID   HEK293-CNG-Slc1a3
AC   CVCL_C0RX
SY   HEK 293-CNG-Slc1a3
DR   Wikidata; Q112929681
CC   Characteristics: Expresses a modified cyclic nucleotide gated (CNG) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization. Allows sensitive detection of signaling by Gs, Gi or Gq-coupled receptors (Dexorgen).
CC   Characteristics: Parental and control cell line for ACTOne GRM2, ACTOne GRM7 and ACTOne GRM8.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:10941; SLC1A3.
CC   Genetic integration: Method=Transduction; Gene=RGD; 2367; Cnga2 (Note=With p.Phe68Ala, p.Trp81Ala, p.Cys460Trp and p.Glu583Met = oCNG-NC).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
CC   Miscellaneous: Has Dexorgen catalog number CB-81200-238, but not distributed separately from children cell lines.
CC   Misspelling: HEK293-CNG-Slcla3; Note=In some Dexorgen (Codex Biosolutions) data sheets.
CC   Misspelling: HEK 293-CNG-Slcla3; Note=In some Dexorgen (Codex Biosolutions) data sheets.
CC   Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C0RU ! HEK293-CNG
SX   Female
AG   Fetus
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 10-04-25; Version: 7
//