ID   RMA-S.Trh4
AC   CVCL_C0DD
DR   CancerTools; 157675
DR   Ximbio; 157675
DR   Wikidata; Q114312801
RX   PubMed=21898382;
RX   PubMed=29399388;
CC   Characteristics: This cell line provides a model to help to understand T-cell recognition through Cers5/Trh4 expression (Ximbio=157675).
CC   Transfected with: MGI; MGI:1919199; Cers5.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transformant: ChEBI; CHEBI:23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
CC   Transformant: NCBI_TaxID; 11938; Rauscher murine leukemia virus (R-MuLV).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: C57BL/6.
DI   NCIt; C21604; Mouse leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_2180 ! RMA-S
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=21898382; DOI=10.1002/eji.201141836;
RA   Oliveira C.C., Querido B.J., Sluijter M., Derbinski J.,
RA   van der Burg S.H., van Hall T.;
RT   "Peptide transporter TAP mediates between competing antigen sources
RT   generating distinct surface MHC class I peptide repertoires.";
RL   Eur. J. Immunol. 41:3114-3124(2011).
//
RX   PubMed=29399388; DOI=10.1080/2162402X.2017.1382793;
RA   Doorduijn E.M., Sluijter M., Marijt K.A., Querido B.J.,
RA   van der Burg S.H., van Hall T.;
RT   "T cells specific for a TAP-independent self-peptide remain naive in
RT   tumor-bearing mice and are fully exploitable for therapy.";
RL   OncoImmunology 7:e1382793.1-e1382793.10(2018).
//