ID   UPCI-SCC-084
AC   CVCL_C047
SY   UPCI:SCC084; SCC084
DR   Cosmic; 1969497
DR   DSMZ; ACC-878
DR   DSMZCellDive; ACC-878
DR   IARC_TP53; 18357
DR   Wikidata; Q54991654
RX   PubMed=12872257;
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=24142626;
RX   PubMed=27045798;
CC   Population: Caucasian.
CC   Doubling time: ~22 hours (DSMZ=ACC-878).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220fs*27 (c.655delC) (p.P219Lfs); Zygosity=Unspecified (PubMed=12872257).
CC   Derived from site: In situ; Oral cavity, retromolar trigone; UBERON=UBERON_0012376.
ST   Source(s): DSMZ=ACC-878
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 9,13
ST   D18S51: 14
ST   D19S433: 14
ST   D21S11: 28
ST   D2S1338: 17
ST   D3S1358: 16
ST   D5S818: 13
ST   D7S820: 9,12
ST   D8S1179: 13,16
ST   FGA: 20
ST   Penta D: 9
ST   Penta E: 11,15
ST   TH01: 6
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C8172; Retromolar trigone squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   52Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 19-12-24; Version: 17
//
RX   PubMed=12872257; DOI=10.1002/humu.10248;
RA   Telmer C.A., An J.-Y., Malehorn D.E., Zeng X.-M., Gollin S.M.,
RA   Ishwad C.S., Jarvik J.W.;
RT   "Detection and assignment of TP53 mutations in tumor DNA using peptide
RT   mass signature genotyping.";
RL   Hum. Mutat. 22:158-165(2003).
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001; PMCID=PMC2025692;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003; PMCID=PMC2362065;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=24142626; DOI=10.1002/gcc.22115; PMCID=PMC5520977;
RA   Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W.,
RA   Vlad A., Gollin S.M.;
RT   "Upregulation of the ATR-CHEK1 pathway in oral squamous cell
RT   carcinomas.";
RL   Genes Chromosomes Cancer 53:25-37(2014).
//
RX   PubMed=27045798; DOI=10.1038/srep23932; PMCID=PMC4820705;
RA   Ghosh R.D., Ghuwalewala S., Das P., Mandloi S., Alam S.K.,
RA   Chakraborty J., Sarkar S., Chakrabarti S., Panda C.K.,
RA   Roychoudhury S.;
RT   "MicroRNA profiling of cisplatin-resistant oral squamous cell
RT   carcinoma cell lines enriched with cancer-stem-cell-like and
RT   epithelial-mesenchymal transition-type features.";
RL   Sci. Rep. 6:23932-23932(2016).
//