ID   MasterShef8
AC   CVCL_BW81
SY   MasterShef 8; MasterShef08; MstrShef8; MShef8; UOSe013-A
DR   BioSamples; SAMEA104627894
DR   hPSCreg; UOSe013-A
DR   Wikidata; Q54904054
RX   PubMed=26607962;
RX   PubMed=27829140;
RX   PubMed=28445466;
CC   Group: Clinical grade pluripotent cell line.
CC   From: University of Sheffield; Sheffield; United Kingdom.
CC   Registration: UK Stem Cell Bank (UKSCB); C-14-025, Steering comm. appl. SCSC12-09.
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Variations; CNV analysis.
CC   Omics: Variations; SNP array analysis.
CC   Donor information: Embryo is sibling to that giving rise to MasterShef5 (Cellosaurus=CVCL_BW78).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 13-07-16; Last updated: 10-04-25; Version: 14
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RX   PubMed=26607962; DOI=10.1038/srep17258; PMCID=PMC4660465;
RA   Canham M.A., Van Deusen A.L., Brison D.R., De Sousa P.A., Downie J.M.,
RA   Devito L.G., Hewitt Z.A., Ilic D., Kimber S.J., Moore H.D., Murray H.,
RA   Kunath T.;
RT   "The molecular karyotype of 25 clinical-grade human embryonic stem
RT   cell lines.";
RL   Sci. Rep. 5:17258.1-17258.13(2015).
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RX   PubMed=27829140; DOI=10.1016/j.stemcr.2016.10.003; PMCID=PMC5106530;
RA   Baker D.E.C., Hirst A.J., Gokhale P.J., Juarez M.A., Williams S.,
RA   Wheeler M., Bean K., Allison T.F., Moore H.D., Andrews P.W.,
RA   Barbaric I.;
RT   "Detecting genetic mosaicism in cultures of human pluripotent stem
RT   cells.";
RL   Stem Cell Reports 7:998-1012(2016).
//
RX   PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.C.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative p53 mutations.";
RL   Nature 545:229-233(2017).
//