ID   LAZ-149
AC   CVCL_BT08
SY   LAZ 149; LAZ149; GM10610
DR   CLO; CLO_0024280
DR   BioSample; SAMN00800101
DR   Coriell; GM10610
DR   Wikidata; Q54901982
RX   CelloPub=CLPUB00447;
RX   PubMed=947544;
RX   PubMed=6196781;
CC   From: Lazarus H.; Dana-Farber Cancer Institute; Boston; USA.
CC   Population: African American.
CC   Sequence variation: Gene deletion; HGNC; 4823; HBA1; Zygosity=Heterozygous (Coriell=GM10610).
CC   Sequence variation: Gene deletion; HGNC; 4827; HBB; Zygosity=Homozygous (Coriell=GM10610).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C34375; Beta thalassemia
DI   ORDO; Orphanet_231214; Beta-thalassemia major
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 02-05-16; Last updated: 30-01-24; Version: 14
//
RX   CelloPub=CLPUB00447;
RA   Mulivor R.A., Suchy S.F.;
RT   "1992/1993 catalog of cell lines. NIGMS human genetic mutant cell
RT   repository. 16th edition. October 1992.";
RL   (In) Institute for Medical Research (Camden, N.J.) NIH 92-2011; pp.1-918; National Institutes of Health; Bethesda (1992).
//
RX   PubMed=947544; DOI=10.1016/0092-8674(76)90161-6;
RA   Forget B.G., Hillman D.G., Lazarus H., Barell E.F., Benz E.J. Jr.,
RA   Caskey C.T., Huisman T.H.J., Schroeder W.A., Housman D.E.;
RT   "Absence of messenger RNA and gene DNA for beta-globin chains in
RT   hereditary persistence of fetal hemoglobin.";
RL   Cell 7:323-329(1976).
//
RX   PubMed=6196781; DOI=10.1073/pnas.80.22.6937;
RA   Tuan D., Feingold E., Newman M., Weissman S.M., Forget B.G.;
RT   "Different 3' end points of deletions causing delta beta-thalassemia
RT   and hereditary persistence of fetal hemoglobin: implications for the
RT   control of gamma-globin gene expression in man.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:6937-6941(1983).
//