ID   ESI-051
AC   CVCL_B858
SY   ESI051; SSCCe005-A
DR   hPSCreg; SSCCe005-A
DR   ISCR; 83
DR   NIHhESC; NIHhESC-11-0131
DR   SKIP; SKIP002089
DR   Wikidata; Q54832760
RX   PubMed=18371388;
RX   PubMed=22265736;
RX   PubMed=28445466;
WW   http://www.esibio.com/products/product-category/cell-lines/esi-051-human-embryonic-stem-cell-line-46-xx/
CC   Group: Clinical grade pluripotent cell line.
CC   From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-11-0131.
CC   Omics: CNV analysis.
CC   Omics: Deep exome analysis.
CC   Omics: Genome sequenced.
CC   Omics: SNP array analysis.
CC   Donor information: Embryo is sibling to that giving rise to ESI-053 (Cellosaurus=CVCL_B859).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): ESI BIO
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 12
ST   D16S539: 11
ST   D18S51: 18
ST   D21S11: 24.2,31.2
ST   D3S1358: 14,16
ST   D5S818: 12,13
ST   D7S820: 11
ST   D8S1179: 10,13
ST   FGA: 20,22.2
ST   Penta D: 9,11
ST   Penta E: 5,17
ST   TH01: 6,7
ST   TPOX: 8,11
ST   vWA: 15,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 02-05-24; Version: 17
//
RX   PubMed=18371388; DOI=10.1016/j.stem.2007.10.004;
RA   Crook J.M., Peura T.T., Kravets L., Bosman A.G., Buzzard J.J.,
RA   Horne R., Hentze H., Dunn N.R., Zweigerdt R., Chua F., Upshall A.,
RA   Colman A.;
RT   "The generation of six clinical-grade human embryonic stem cell
RT   lines.";
RL   Cell Stem Cell 1:490-494(2007).
//
RX   PubMed=22265736; DOI=10.1016/j.scr.2011.10.001;
RA   Funk W.D., Labat I., Sampathkumar J., Gourraud P.-A., Oksenberg J.R.,
RA   Rosler E.S., Steiger D., Sheibani N., Caillier S., Stache-Crain B.,
RA   Johnson J.A., Meisner L.F., Lacher M.D., Chapman K.B., Park M.J.,
RA   Shin K.-J., Drmanac R., West M.D.;
RT   "Evaluating the genomic and sequence integrity of human ES cell lines;
RT   comparison to normal genomes.";
RL   Stem Cell Res. 8:154-164(2012).
//
RX   PubMed=28445466; DOI=10.1038/nature22312;
RA   Merkle F.T., Ghosh S., Kamitaki N., Mitchell J., Avior Y., Mello C.,
RA   Kashin S., Mekhoubad S., Ilic D., Charlton M., Saphier G.,
RA   Handsaker R.E., Genovese G., Bar S., Benvenisty N., McCarroll S.A.,
RA   Eggan K.C.;
RT   "Human pluripotent stem cells recurrently acquire and expand dominant
RT   negative P53 mutations.";
RL   Nature 545:229-233(2017).
//