ID   e-hLEC-1
AC   CVCL_B7U4
DR   Wikidata; Q112929478
RX   PubMed=29520052;
CC   Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=29520052).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:3796; FOS.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6348; KLF4.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Endothelial cell of lymphatic vessel; CL=CL_0002138.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_B7U5 ! e-hLEC-2
CA   Transformed cell line
DT   Created: 23-06-22; Last updated: 10-04-25; Version: 7
//
RX   PubMed=29520052; DOI=10.1038/s41467-018-03408-4; PMCID=PMC5843645;
RA   Lipps C., Klein F., Wahlicht T., Seiffert V., Butueva M., Zauers J.,
RA   Truschel T., Luckner M., Koster M., MacLeod R.A.F., Pezoldt J., Huhn J.,
RA   Yuan Q.-G., Muller P.P., Kempf H., Zweigerdt R., Dittrich-Breiholz O.,
RA   Pufe T., Beckmann R., Drescher W., Riancho J.A., Sanudo C., Korff T.,
RA   Opalka B., Rebmann V., Gothert J.R., Alves P.M., Ott M., Schucht R.,
RA   Hauser H., Wirth D., May T.;
RT   "Expansion of functional personalized cells with specific transgene
RT   combinations.";
RL   Nat. Commun. 9:994.1-994.12(2018).
//