ID   ACN/IFN-gamma
AC   CVCL_B7TC
DR   cancercelllines; CVCL_B7TC
DR   Wikidata; Q112929124
RX   PubMed=15150552;
CC   Problematic cell line: Probably contaminated. Parent cell line (ACN) has been shown to probably be a melanoma cell line.
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9588; PTEN; Simple; p.Asn184fs*6 (c.545_546insA); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Phe113Ser (c.338T>C); ClinVar=VCV000823709; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 5438; IFNG.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1068 ! ACN
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 4
//
RX   PubMed=15150552; DOI=10.1038/sj.bjc.6601842;
RA   Airoldi I., Meazza R., Croce M., Di Carlo E., Piazza T., Cocco C.,
RA   D'Antuono T., Pistoia V., Ferrini S., Corrias M.V.;
RT   "Low-dose interferon-gamma-producing human neuroblastoma cells show
RT   reduced proliferation and delayed tumorigenicity.";
RL   Br. J. Cancer 90:2210-2218(2004).
//