ID   PC9/TS2
AC   CVCL_B7NA
DR   cancercelllines; CVCL_B7NA
DR   Wikidata; Q112930292
RX   PubMed=21487406;
CC   Population: Chinese; Han and Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:12441; TYMS.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B260 ! PC-9
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 7
//
RX   PubMed=21487406; DOI=10.1038/bjc.2011.129; PMCID=PMC3101907;
RA   Takezawa, Ken
RA   Okamoto, I.
RA   Okamoto, Wataru
RA   Takeda, M.
RA   Sakai, K.
RA   Tsukioka, Sayaka
RA   Kuwata, Kiyoko
RA   Yamaguchi, H.
RA   Nishio, K.
RA   Nakagawa, K.
RT   "Thymidylate synthase as a determinant of pemetrexed sensitivity in
RT   non-small cell lung cancer.";
RL   Br. J. Cancer 104:1594-1601(2011).
//