ID   PC9/TS1
AC   CVCL_B7N9
DR   cancercelllines; CVCL_B7N9
DR   Wikidata; Q112930291
RX   PubMed=21487406;
CC   Population: Chinese; Han and Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:12441; TYMS.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B260 ! PC-9
SX   Male
AG   45Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 19-12-24; Version: 7
//
RX   PubMed=21487406; DOI=10.1038/bjc.2011.129; PMCID=PMC3101907;
RA   Takezawa K., Okamoto I., Okamoto W., Takeda M., Sakai K., Tsukioka S.,
RA   Kuwata K., Yamaguchi H., Nishio K., Nakagawa K.;
RT   "Thymidylate synthase as a determinant of pemetrexed sensitivity in
RT   non-small cell lung cancer.";
RL   Br. J. Cancer 104:1594-1601(2011).
//