ID   HEp-2/VCR
AC   CVCL_B7H7
DR   Wikidata; Q112929711
RX   PubMed=29483928;
CC   Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1906 ! HEp-2
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 10-04-25; Version: 7
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RX   PubMed=29483928; DOI=10.1186/s11658-017-0067-8; PMCID=PMC5819209;
RA   Li, Guo-Dong
RA   Hu, Xiao-Ling
RA   Sun, Lu
RA   Li, Xin
RA   Li, Jian-Feng
RA   Li, Tong-Li
RA   Zhang, Xiao-Hui
RT   "C-fos upregulates P-glycoprotein, contributing to the development of
RT   multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced
RT   resistance.";
RL   Cell. Mol. Biol. Lett. 23:6.1-6.12(2018).
//