ID   HEp-2/VCR
AC   CVCL_B7H7
DR   Wikidata; Q112929711
RX   PubMed=29483928;
CC   Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative.
CC   Population: African American.
CC   Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
DI   NCIt; C27677; Human papillomavirus-related cervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1906 ! HEp-2
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
//
RX   PubMed=29483928; DOI=10.1186/s11658-017-0067-8;
RA   Li G.-D., Hu X.-L., Sun L., Li X., Li J.-F., Li T.-L., Zhang X.-H.;
RT   "C-fos upregulates P-glycoprotein, contributing to the development of
RT   multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced
RT   resistance.";
RL   Cell. Mol. Biol. Lett. 23:6.1-6.12(2018).
//