ID   TIME.219
AC   CVCL_B6YR
DR   Wikidata; Q112041790
RX   PubMed=33937098;
CC   Characteristics: rKSHV.219 includes a RFP-GFP-Puro construct that contains RFP under the control of the lytic PAN RNA promoter, GFP under the control of human EF1a promoter and PuroR expressed by the RSV promoter.
CC   Virology: Infected with a recombinant human herpesvirus 8 (HHV-8/KSHV) rKSHV.219.
CC   Transfected with: HGNC; 11730; TERT.
CC   Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
CC   Transfected with: UniProtKB; Q9U6Y8; Discosoma sp. red fluorescent protein drFP583 (DsRed, RFP).
CC   Transfected with: UniProtKB; P33967; B.cereus Bsr.
CC   Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Derived from site: In situ; Foreskin, skin, dermis, microvascular endothelium; UBERON=UBERON_0001471+UBERON_0008339.
ST   Source(s): PubMed=33937098
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9,11
ST   D16S539: 9,12
ST   D5S818: 11
ST   D7S820: 8,9
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 16,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0047 ! TIME
SX   Male
AG   <1M
CA   Telomerase immortalized cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 6
//
RX   PubMed=33937098; DOI=10.3389/fcimb.2021.654396;
RA   Dollery S.J., Maldonado T.D., Brenner E.A., Berger E.A.;
RT   "iTIME.219: an immortalized KSHV infected endothelial cell line
RT   inducible by a KSHV-specific stimulus to transition from latency to
RT   lytic replication and infectious virus release.";
RL   Front. Cell. Infect. Microbiol. 11:654396.1-654396.9(2021).
//