ID   EL4B7-1
AC   CVCL_B6PG
SY   EL4-B7-1; B7-1-EL4; B7-EL-4
DR   Wikidata; Q111733184
RX   PubMed=7527298;
RX   PubMed=10075975;
RX   PubMed=10477562;
CC   Transfected with: MGI; MGI:101775; Cd80.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: ChEBI; CHEBI:59032; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
CC   Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
CC   Cell type: T-cell; CL=CL_0000084.
CC   Breed/subspecies: C57BL/6N.
DI   NCIt; C21925; Mouse precursor T cell lymphoblastic lymphoma/leukemia
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0255 ! EL4
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 5
//
RX   PubMed=7527298;
RA   Townsend S.E., Su F.W., Atherton J.M., Allison J.P.;
RT   "Specificity and longevity of antitumor immune responses induced by
RT   B7-transfected tumors.";
RL   Cancer Res. 54:6477-6483(1994).
//
RX   PubMed=10075975; DOI=10.1084/jem.189.6.919;
RA   Stremmel C., Greenfield E.A., Howard E., Freeman G.J., Kuchroo V.K.;
RT   "B7-2 expressed on EL4 lymphoma suppresses antitumor immunity by an
RT   interleukin 4-dependent mechanism.";
RL   J. Exp. Med. 189:919-930(1999).
//
RX   PubMed=10477562; DOI=10.4049/jimmunol.163.6.2999;
RA   Krummel M.F., Heath W.R., Allison J.;
RT   "Differential coupling of second signals for cytotoxicity and
RT   proliferation in CD8+ T cell effectors: amplification of the lytic
RT   potential by B7.";
RL   J. Immunol. 163:2999-3006(1999).
//