ID   Mel Rac
AC   CVCL_B6KA
SY   mel Rac
DR   cancercelllines; CVCL_B6KA
DR   Wikidata; Q112129308
RX   CelloPub=CLPUB00680;
RX   DOI=10.17650/1726-9784-2018-17-4-27-35;
RX   Patent=RU2402602;
RX   PubMed=28881731;
CC   Group: Patented cell line.
CC   Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 710D.
CC   HLA typing: A*23,26; B*08,39 (Patent=RU2402602).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Unspecified (DOI=10.17650/1726-9784-2018-17-4-27-35; PubMed=28881731).
CC   Derived from site: Metastatic; Right thigh, hypodermis; UBERON=UBERON_0000376+UBERON_0002072.
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 14-08-25; Version: 8
//
RX   PubMed=28881731; DOI=10.18632/oncotarget.17014; PMCID=PMC5581030;
RA   Emelyanova, Marina
RA   Ghukasyan, Lilit
RA   Abramov, Ivan
RA   Ryabaya, Oxana
RA   Stepanova, Evgenia Vladislavovna
RA   Kudryavtseva, Anna Viktorovna
RA   Sadritdinova, Asiya
RA   Dzhumakova, Cholpon
RA   Belysheva, Tatiana
RA   Surzhikov, Sergey
RA   Lyubchenko, Lyudmila
RA   Zasedatelev, Alexander
RA   Nasedkina, Tatiana
RT   "Detection of BRAF, NRAS, KIT, GNAQ, GNA11 and MAP2K1/2 mutations in
RT   Russian melanoma patients using LNA PCR clamp and biochip analysis.";
RL   Oncotarget 8:52304-52320(2017).
//
RX   CelloPub=CLPUB00680;
RA   Mikhailova, Irina Nikolaevna
RA   Baryshnikov, Anatoly Yurievich
RA   Morozova, Lidia Fyodorovna
RA   Burova, Olga Semyonovna
RA   Shubina, Irina Zhanovna
RA   Kovalevsky, Dmitry A.
RA   Voronina, Ekaterina Sergeevna
RA   Treshalina, Helena Mikhailovna
RA   Lushnikova, Anna A.
RA   Tsyganova, Irina V.
RA   Mazurenko, Natalia N.
RT   "Human skin melanoma cell lines collection.";
RL   (In book chapter) Management of malignant melanoma; No_last_name, No_first_name (eds.); pp.6.1-6.6; SM Group; Dover; USA (2016).
//
RX   DOI=10.17650/1726-9784-2018-17-4-27-35;
RA   Mikhailova, Irina Nikolaevna
RA   Treshalina, Helena Mikhailovna
RA   Morozova, Lidia Fyodorovna
RA   Andronova, Nataliya V.
RA   Shubina, Irina Zhanovna
RA   Lushnikova, Anna A.
RT   "Cell lines of human melanoma and their xenograft with BRAF or NRAS
RT   mutations a targets for targeted therapy.";
RL   Ross. Bioterap. Zh. 17:27-35(2018).
//
RX   Patent=RU2402602;
RA   Mikhailova, Irina Nikolaevna
RA   Baryshnikov, Anatoly Yurievich
RA   Demidov, Lev Vadimovich
RA   Kiselev, Sergey L'vovich
RA   Burova, Olga Semyonovna
RA   Morozova, Lidia Fyodorovna
RT   "Cell line of human melanoma mel Rac, applied for obtaining
RT   antitumour vaccine.";
RL   Patent number RU2402602, 27-Oct-2010.
//