ID   BV1
AC   CVCL_B6F9
DR   Wikidata; Q111733024
RX   PubMed=10762059;
CC   Characteristics: Proliferates at the permissive temperature (33 Celsius). Rapid decrease in cell proliferation at the restrictive temperature (39 Celsius) (PubMed=10762059).
CC   Doubling time: 33.4 hours (Note=At 15th passage), 17.8 hours (Note=At 50th passage) (PubMed=10762059).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
CC   Breed/subspecies: Brown Norway; RS=RS_0000113.
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
SX   Male
AG   Adult
CA   Conditionally immortalized cell line
DT   Created: 17-03-22; Last updated: 14-08-25; Version: 9
//
RX   PubMed=10762059; DOI=10.1038/emm.2000.6;
RA   Kim, Byung-Ho
RA   Sung, Se-Ra
RA   Choi, Eun-Hee
RA   Kim, Young-Il
RA   Kim, Kyeong-Jin
RA   Dong, Seok-Ho
RA   Kim, Hyo-Jong
RA   Chang, Young-Woon
RA   Lee, Joung-Il
RA   Chang, Rin
RT   "Dedifferentiation of conditionally immortalized hepatocytes with
RT   long-term in vitro passage.";
RL   Exp. Mol. Med. 32:29-37(2000).
//