ID   HL-60 clone H6
AC   CVCL_B6DS
SY   H6
DR   cancercelllines; CVCL_B6DS
DR   Wikidata; Q111733433
RX   PubMed=1368402;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_16134; Ammonia.
CC   Selected for resistance to: ChEBI; CHEBI_24996; Lactate.
CC   Sequence variation: Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7961; Adult acute myeloid leukemia with maturation
DI   ORDO; Orphanet_98834; Acute myeloblastic leukemia with maturation
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0002 ! HL-60
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 14-08-25; Version: 7
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RX   PubMed=1368402; DOI=10.1007/BF02540028;
RA   Schumpp-Vonach, Benedicte
RA   Schlaeger, Ernst-Juergen
RT   "Growth study of lactate and ammonia double-resistant clones of HL-60
RT   cells.";
RL   Cytotechnology 8:39-44(1992).
//