ID   IM-9-P6
DR   Wikidata; Q111733502
RX   PubMed=1324146;
RX   PubMed=1366653;
RX   PubMed=2836165;
CC   Problematic cell line: Misclassified. Grand-parent cell line originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
CC   Population: Caucasian.
CC   Characteristics: Compared to the parent cell line, has lost the ability to produces prolactin.
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 5
RX   PubMed=1324146; DOI=10.1210/endo.131.3.1324146;
RA   Gellersen B., Kempf R., Hartung S., Bonhoff A., DiMattia G.E.;
RT   "Posttranscriptional regulation of the human prolactin gene in IM-9-P3
RT   cells by retinoic acid.";
RL   Endocrinology 131:1017-1025(1992).
RX   PubMed=1366653; DOI=10.1007/BF00365265;
RA   Bonhoff A., Gellersen B., Held K.R., Bohnet H.G.;
RT   "Clonal derivatives of a human B-lymphoblastoid cell line producing
RT   prolactin -- a cytogenetic characterization.";
RL   Cytotechnology 3:43-50(1990).
RX   PubMed=2836165; DOI=10.1210/endo-122-6-2508;
RA   DiMattia G.E., Gellersen B., Bohnet H.G., Friesen H.G.;
RT   "A human B-lymphoblastoid cell line produces prolactin.";
RL   Endocrinology 122:2508-2517(1988).