ID   IM-9-P3
AC   CVCL_B6CW
DR   Wikidata; Q111733498
RX   PubMed=1324146;
RX   PubMed=1366653;
RX   PubMed=1697858;
RX   PubMed=2836165;
CC   Problematic cell line: Misclassified. Grand-parent cell line originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
CC   Population: Caucasian.
CC   Characteristics: Produces prolactin.
CC   Sequence variation: Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B6CV ! IM-9-P
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 5
CH   CVCL_B6CZ ! IM-9-P31
CH   CVCL_B6D0 ! IM-9-P32
CH   CVCL_B6CY ! IM-9-P33
//
RX   PubMed=1324146; DOI=10.1210/endo.131.3.1324146;
RA   Gellersen, Birgit
RA   Kempf, Rita
RA   Hartung, Stefan
RA   Bonhoff, Annette
RA   DiMattia, Gabriel E.
RT   "Posttranscriptional regulation of the human prolactin gene in IM-9-P3
RT   cells by retinoic acid.";
RL   Endocrinology 131:1017-1025(1992).
//
RX   PubMed=1366653; DOI=10.1007/BF00365265;
RA   Bonhoff, Annette
RA   Gellersen, Birgit
RA   Held, Karsten R.
RA   Bohnet, Heinz G.
RT   "Clonal derivatives of a human B-lymphoblastoid cell line producing
RT   prolactin -- a cytogenetic characterization.";
RL   Cytotechnology 3:43-50(1990).
//
RX   PubMed=1697858; DOI=10.1016/S0021-9258(17)46238-7;
RA   DiMattia, Gabriel E.
RA   Gellersen, Birgit
RA   Duckworth, Mary Lynn
RA   Friesen, Henry George
RT   "Human prolactin gene expression. The use of an alternative noncoding
RT   exon in decidua and the IM-9-P3 lymphoblast cell line.";
RL   J. Biol. Chem. 265:16412-16421(1990).
//
RX   PubMed=2836165; DOI=10.1210/endo-122-6-2508;
RA   DiMattia, Gabriel E.
RA   Gellersen, Birgit
RA   Bohnet, Heinz G.
RA   Friesen, Henry George
RT   "A human B-lymphoblastoid cell line produces prolactin.";
RL   Endocrinology 122:2508-2517(1988).
//