ID   IM-9-P
DR   Wikidata; Q111733497
RX   PubMed=1366653;
RX   PubMed=1697858;
RX   PubMed=2836165;
CC   Problematic cell line: Misclassified. Parent cell line originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line.
CC   Population: Caucasian.
CC   Characteristics: Produces prolactin. But after approximately 7 months in culture the capacity to synthesize prolactin is greatly reduced (PubMed=1366653; PubMed=2836165).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1305 ! IM-9
SX   Female
AG   Age unspecified
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 4
RX   PubMed=1366653; DOI=10.1007/BF00365265;
RA   Bonhoff A., Gellersen B., Held K.R., Bohnet H.G.;
RT   "Clonal derivatives of a human B-lymphoblastoid cell line producing
RT   prolactin -- a cytogenetic characterization.";
RL   Cytotechnology 3:43-50(1990).
RX   PubMed=1697858; DOI=10.1016/S0021-9258(17)46238-7;
RA   DiMattia G.E., Gellersen B., Duckworth M.L., Friesen H.G.;
RT   "Human prolactin gene expression. The use of an alternative noncoding
RT   exon in decidua and the IM-9-P3 lymphoblast cell line.";
RL   J. Biol. Chem. 265:16412-16421(1990).
RX   PubMed=2836165; DOI=10.1210/endo-122-6-2508;
RA   DiMattia G.E., Gellersen B., Bohnet H.G., Friesen H.G.;
RT   "A human B-lymphoblastoid cell line produces prolactin.";
RL   Endocrinology 122:2508-2517(1988).