ID   BALB/3T3 clone A31 THO2
AC   CVCL_B5VI
SY   THO2; THO-2
DR   Wikidata; Q111732947
RX   PubMed=701383;
RX   PubMed=1028169;
RX   PubMed=6933701;
CC   Characteristics: Deficient in hypoxanthine-guanine phosphoribosyltransferase (HGPRT).
CC   Doubling time: 30 hours (PubMed=1028169); 16 hours (Note=In 10% FBS), 20.4 hours (Note=In 1% FBS) (PubMed=701383).
CC   Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
CC   Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
CC   Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
CC   Breed/subspecies: BALB/c.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B5VH ! BALB/3T3 clone A31 NTG2
SX   Sex unspecified
AG   14-17FD
CA   Transformed cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 5
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RX   PubMed=701383; DOI=10.1002/jcp.1040970203;
RA   Jha K.K., Cacciapuoti J., Ozer H.L.;
RT   "Expression of transformation in cell hybrids. II. Nonsuppression of
RT   the transformed phenotype in hybrids between a chemically transformed
RT   and nontransformed derivatives of Balb/3T3.";
RL   J. Cell. Physiol. 97:147-152(1978).
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RX   PubMed=1028169; DOI=10.1007/BF01538960;
RA   Jha K.K., Ozer H.L.;
RT   "Expression of transformation in cell hybrids. I. Isolation and
RT   application of density-inhibited Balb/3T3 cells deficient in
RT   hypoxanthine phosphoribosyltransferase and resistant to ouabain.";
RL   Somatic Cell Genet. 2:215-223(1976).
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RX   PubMed=6933701; DOI=10.1007/BF01538640;
RA   Jha K.K., Siniscalco M., Ozer H.L.;
RT   "Temperature-sensitive mutants of Balb/3T3 cells. III. Hybrids between
RT   ts2 and other mouse mutant cells affected in DNA synthesis and
RT   correction of ts2 defect by human X chromosome.";
RL   Somatic Cell Genet. 6:603-614(1980).
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