ID   MCF7-FGFR1
AC   CVCL_B5PF
SY   MCF7-R1
DR   cancercelllines; CVCL_B5PF
DR   Wikidata; Q112930094
RX   PubMed=34542998;
WW   Provider; I2B; P-101; http://inven2biologics.com/shop/cell-lines/human/mcf7-fgfr1-breast-cancer-cell-line-0
CC   Population: Caucasian.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3688; FGFR1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 10-04-25; Version: 8
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RX   PubMed=34542998; DOI=10.1021/acs.biomac.1c00662; PMCID=PMC8512659;
RA   Krzyscik M.A., Zakrzewska M., Sorensen V., Oy G.F., Brunheim S.,
RA   Haugsten E.M., Maelandsmo G.M., Wiedlocha A., Otlewski J.;
RT   "Fibroblast growth factor 2 conjugated with monomethyl auristatin e
RT   inhibits tumor growth in a mouse model.";
RL   Biomacromolecules 22:4169-4180(2021).
//