ID   88.6/D800-B
AC   CVCL_B5P1
SY   D800-B
DR   Wikidata; Q111732824
RX   PubMed=11956086;
CC   Knockout cell: Method=KO mouse; MGI; MGI:97570; Abcb1a.
CC   Knockout cell: Method=KO mouse; MGI; MGI:97568; Abcb1b.
CC   Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
CC   Sequence variation: Mutation; MGI; MGI:1347061; Abcg2; Simple; p.Arg482Ser (c.1446G>T); Zygosity=Homozygous (PubMed=11956086).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_B5NX ! 88.6
SX   Sex unspecified
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 17-03-22; Last updated: 19-12-24; Version: 5
//
RX   PubMed=11956086;
RA   Allen J.D., Jackson S.C., Schinkel A.H.;
RT   "A mutation hot spot in the Bcrp1 (Abcg2) multidrug transporter in
RT   mouse cell lines selected for doxorubicin resistance.";
RL   Cancer Res. 62:2294-2299(2002).
//