ID   HGS2
AC   CVCL_B5GW
DR   CancerTools; 160538
DR   Wikidata; Q110432893
DR   Ximbio; 160538
RX   PubMed=31940494;
CC   Characteristics: When injected i.p. produces omental tumors and metastases to splenoportal fat, lesser omentum, and mesentery, with extensive disease established by 12-20 weeks (PubMed=31940494).
CC   Knockout cell: Method=KO mouse; MGI; MGI:109337; Brca2.
CC   Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten.
CC   Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53.
CC   Derived from site: In situ; Fallopian tube; UBERON=UBERON_0003889.
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Breed/subspecies: B6.129P2-Trp53tm1Brn/J.Ptenfl/f x C57BL/6J-Brca2fl/fl.
DI   NCIt; C33903; Mouse ovarian serous adenocarcinoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 14-08-25; Version: 8
//
RX   PubMed=31940494; DOI=10.1016/j.celrep.2019.12.034; PMCID=PMC6963791;
RA   Maniati, Eleni
RA   Berlato, Chiara
RA   Gopinathan, Ganga
RA   Heath, Owen
RA   Kotantaki, Panoraia
RA   Lakhani, Anissa
RA   McDermott, Jacqueline
RA   Pegrum, Colin
RA   Delaine-Smith, Robin M.
RA   Pearce, Oliver M.T.
RA   Hirani, Priyanka
RA   Joy, Joash D.
RA   Szabova, Ludmila
RA   Perets, Ruth
RA   Sansom, Owen James
RA   Drapkin, Ronny I.
RA   Bailey, Peter
RA   Balkwill, Frances Rosemary
RT   "Mouse ovarian cancer models recapitulate the human tumor
RT   microenvironment and patient response to treatment.";
RL   Cell Rep. 30:525-540.e7(2020).
//