ID   253G1
AC   CVCL_B518
SY   253-G1; HiPS253G1; HPS0002
DR   GEO; GSM1040251
DR   GEO; GSM1040321
DR   GEO; GSM1489219
DR   GEO; GSM1489425
DR   RCB; HPS0002
DR   SKIP; SKIP000002
DR   Wikidata; Q54583649
RX   PubMed=18059259;
RX   PubMed=21098095;
RX   PubMed=22056147;
RX   PubMed=22802639;
RX   PubMed=24259714;
RX   PubMed=27476965;
RX   PubMed=27806289;
RX   PubMed=28453617;
CC   From: Center for iPS Cell Research and Application, Kyoto University; Kyoto; Japan.
CC   Population: Caucasian.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
CC   Cell type: Fibroblast of skin; CL=CL_0002620.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_DP59 ! HDF1388
SX   Female
AG   36Y
CA   Induced pluripotent stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 15
//
RX   PubMed=18059259; DOI=10.1038/nbt1374;
RA   Nakagawa M., Koyanagi M., Tanabe K., Takahashi K., Ichisaka T.,
RA   Aoi T., Okita K., Mochiduki Y., Takizawa N., Yamanaka S.;
RT   "Generation of induced pluripotent stem cells without Myc from mouse
RT   and human fibroblasts.";
RL   Nat. Biotechnol. 26:101-106(2008).
//
RX   PubMed=21098095; DOI=10.1084/jem.20100844;
RA   Takayama N., Nishimura S., Nakamura S., Shimizu T., Ohnishi R.,
RA   Endo H., Yamaguchi T., Otsu M., Nishimura K., Nakanishi M.,
RA   Sawaguchi A., Nagai R., Takahashi K., Yamanaka S., Nakauchi H.,
RA   Eto K.;
RT   "Transient activation of c-MYC expression is critical for efficient
RT   platelet generation from human induced pluripotent stem cells.";
RL   J. Exp. Med. 207:2817-2830(2010).
//
RX   PubMed=22056147; DOI=10.1016/j.scr.2011.10.002;
RA   Kunisada Y., Tsubooka-Yamazoe N., Shoji M., Hosoya M.;
RT   "Small molecules induce efficient differentiation into
RT   insulin-producing cells from human induced pluripotent stem cells.";
RL   Stem Cell Res. 8:274-284(2012).
//
RX   PubMed=22802639; DOI=10.1073/pnas.1209979109;
RA   Kajiwara M., Aoi T., Okita K., Takahashi R., Inoue H., Takayama N.,
RA   Endo H., Eto K., Toguchida J., Uemoto S., Yamanaka S.;
RT   "Donor-dependent variations in hepatic differentiation from
RT   human-induced pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12538-12543(2012).
//
RX   PubMed=24259714; DOI=10.1073/pnas.1319061110;
RA   Koyanagi-Aoi M., Ohnuki M., Takahashi K., Okita K., Noma H.,
RA   Sawamura Y., Teramoto I., Narita M., Sato Y., Ichisaka T., Amano N.,
RA   Watanabe A., Morizane A., Yamada Y., Sato T., Takahashi J.,
RA   Yamanaka S.;
RT   "Differentiation-defective phenotypes revealed by large-scale analyses
RT   of human pluripotent stem cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20569-20574(2013).
//
RX   PubMed=27476965; DOI=10.1016/j.stem.2016.06.019;
RA   Nishizawa M., Chonabayashi K., Nomura M., Tanaka A., Nakamura M.,
RA   Inagaki A., Nishikawa M., Takei I., Oishi A., Tanabe K., Ohnuki M.,
RA   Yokota H., Koyanagi-Aoi M., Okita K., Watanabe A., Takaori-Kondo A.,
RA   Yamanaka S., Yoshida Y.;
RT   "Epigenetic variation between human induced pluripotent stem cell
RT   lines is an indicator of differentiation capacity.";
RL   Cell Stem Cell 19:341-354(2016).
//
RX   PubMed=27806289; DOI=10.1016/j.celrep.2016.10.026;
RA   Ishida Y., Kawakami H., Kitajima H., Nishiyama A., Sasai Y., Inoue H.,
RA   Muguruma K.;
RT   "Vulnerability of Purkinje cells generated from spinocerebellar ataxia
RT   type 6 patient-derived iPSCs.";
RL   Cell Rep. 17:1482-1490(2016).
//
RX   PubMed=28453617; DOI=10.1093/biolre/iox038;
RA   Yokobayashi S., Okita K., Nakagawa M., Nakamura T., Yabuta Y.,
RA   Yamamoto T., Saitou M.;
RT   "Clonal variation of human induced pluripotent stem cells for
RT   induction into the germ cell fate.";
RL   Biol. Reprod. 96:1154-1166(2017).
//