ID   G523
AC   CVCL_B4P6
SY   G523NS
DR   EGA; EGAS00001003493
DR   EGA; EGAS00001003700
DR   GEO; GSM3439929
DR   GEO; GSM3439930
DR   GEO; GSM3439931
DR   GEO; GSM3439938
DR   GEO; GSM3439939
DR   GEO; GSM3439940
DR   Wikidata; Q110432806
RX   PubMed=30995489;
RX   PubMed=31249064;
RX   PubMed=36989359;
RX   PubMed=38089093;
CC   Group: Cancer stem cell line.
CC   Omics: Genomics; ChIP-seq; CTCF.
CC   Omics: Genomics; ChIP-seq; H3K27ac.
CC   Omics: Genomics; Chromosome conformation analysis; Hi-C.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 14-08-25; Version: 7
CH   CVCL_C9AB ! G523NS-Cas9
//
RX   PubMed=36989359; DOI=10.1126/sciadv.ade5321; PMCID=PMC10058241;
RA   Wang, Xian
RA   Gong, Zhe-Yuan
RA   Wang, Tian-Cong
RA   Law, Jun-Hui
RA   Chen, Xin
RA   Wanggou, Si-Yi
RA   Wang, Jin-Tian
RA   Ying, Bin-Bin
RA   Francisco, Michelle A.
RA   Dong, Wei-Fan
RA   Xiong, Yi
RA   Fan, Jerry J.
RA   MacLeod, Graham
RA   Angers, Stephane
RA   Li, Xue-Jun
RA   Dirks, Peter Benjamin
RA   Liu, Xin-Yu
RA   Huang, Xi
RA   Sun, Yu
RT   "Mechanical nanosurgery of chemoresistant glioblastoma using
RT   magnetically controlled carbon nanotubes.";
RL   Sci. Adv. 9:eade5321.1-eade5321.14(2023).
//
RX   PubMed=38089093; DOI=10.1021/acsmaterialsau.3c00029; PMCID=PMC10510514;
RA   Smith, Laura J.
RA   Skirzynska, Arianna
RA   Chin, Allysia A.
RA   Arnold, Amy E.
RA   Kushida, Michelle M.
RA   Dirks, Peter Benjamin
RA   Shoichet, Molly S.
RT   "Engineered in vitro tumor model recapitulates molecular signatures of
RT   invasion in glioblastoma.";
RL   ACS Materials Au 3:514-527(2023).
//
RX   PubMed=30995489; DOI=10.1016/j.celrep.2019.03.047;
RA   MacLeod, Graham
RA   Bozek, Danielle Anne
RA   Rajakulendran, Nishani
RA   Monteiro, Vernon
RA   Ahmadi, Moloud
RA   Steinhart, Zachary
RA   Kushida, Michelle M.
RA   Yu, Helen
RA   Coutinho, Fiona J.
RA   Cavalli, Florence M.G.
RA   Restall, Ian J.
RA   Hao, Xiao-Guang
RA   Hart, Traver
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RA   Dirks, Peter Benjamin
RA   Angers, Stephane
RT   "Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and
RT   mechanisms of temozolomide sensitivity in glioblastoma stem cells.";
RL   Cell Rep. 27:971-986.e9(2019).
//
RX   PubMed=31249064; DOI=10.1101/gr.246520.118; PMCID=PMC6673710;
RA   Johnston, Michael J.
RA   Nikolic, Ana
RA   Ninkovic, Nicoletta Alexandra
RA   Guilhamon, Paul
RA   Cavalli, Florence M.G.
RA   Seaman, Steven
RA   Zemp, Franz J.
RA   Lee, John
RA   Abdelkareem, Aly
RA   Ellestad, Katrina
RA   Murison, Alex
RA   Kushida, Michelle M.
RA   Coutinho, Fiona J.
RA   Ma, Yussanne
RA   Mungall, Andrew J.
RA   Moore, Richard
RA   Marra, Marco Antonio
RA   Taylor, Michael D.
RA   Dirks, Peter Benjamin
RA   Pugh, Trevor J.
RA   Morrissy, Anca Sorana
RA   St Croix, Bradley
RA   Mahoney, Douglas J.
RA   Lupien, Mathieu
RA   Gallo, Marco
RT   "High-resolution structural genomics reveals new therapeutic
RT   vulnerabilities in glioblastoma.";
RL   Genome Res. 29:1211-1222(2019).
//