ID   4T1.3
AC   CVCL_B3QZ
DR   Wikidata; Q110429789
RX   PubMed=27177471;
RX   PubMed=34632664;
CC   Characteristics: Metastasizes with high frequency to bone upon orthotopic injection into the mammary fat pad of immunocompetent female BALB/c mice (PubMed=27177471).
CC   Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
CC   Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
CC   Breed/subspecies: BALB/cfC3H.
DI   NCIt; C21678; Malignant neoplasms of the mouse mammary gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
HI   CVCL_0125 ! 4T1
SX   Female
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 29-06-23; Version: 4
//
RX   PubMed=27177471; DOI=10.1016/j.canlet.2016.05.005;
RA   Sasaki S.-i., Baba T., Nishimura T., Hayakawa Y., Hashimoto S.-i.,
RA   Gotoh N., Mukaida N.;
RT   "Essential roles of the interaction between cancer cell-derived
RT   chemokine, CCL4, and intra-bone CCR5-expressing fibroblasts in breast
RT   cancer bone metastasis.";
RL   Cancer Lett. 378:23-32(2016).
//
RX   PubMed=34632664; DOI=10.1111/cas.15150;
RA   Sasaki S.-i., Zhang D., Iwabuchi S., Tanabe Y., Hashimoto S.-i.,
RA   Yamauchi A., Hayashi K., Tsuchiya H., Hayakawa Y., Baba T.,
RA   Mukaida N.;
RT   "Crucial contribution of GPR56/ADGRG1, expressed by breast cancer
RT   cells, to bone metastasis formation.";
RL   Cancer Sci. 112:4883-4893(2021).
//