ID   JEI-001
AC   CVCL_B3MS
SY   Jiaotong Ear Institute-001
DR   CCRID; 4201PAT-CCTCC01456
DR   Wikidata; Q110432994
RX   Patent=CN110904051B;
RX   PubMed=34539995;
RX   PubMed=35359340;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2019182.
CC   Population: Chinese.
CC   Sequence variation: Mutation; HGNC; HGNC:7773; NF2; Simple; c.515delG; Zygosity=Heterozygous (PubMed=34539995).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Peripheral nervous system, vestibular nerve; UBERON=UBERON_0003723.
CC   Cell type: Schwann cell; CL=CL_0002573.
ST   Source(s): PubMed=34539995
ST   Amelogenin: X,Y
ST   CSF1PO: 10,14
ST   D12S391: 17,18
ST   D13S317: 8,11
ST   D16S539: 9,12
ST   D18S51: 14
ST   D19S433: 15,15.2
ST   D21S11: 29
ST   D2S1338: 19,20
ST   D3S1358: 16,17
ST   D5S818: 10,12
ST   D6S1043: 11,20
ST   D7S820: 10,12
ST   D8S1179: 15,16
ST   FGA: 22,23
ST   Penta D: 9.1,11
ST   Penta E: 16,23
ST   TH01: 9
ST   TPOX: 11,12
ST   vWA: 15,19
DI   NCIt; C3276; Vestibular schwannoma
DI   ORDO; Orphanet_252175; Vestibular schwannoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   41Y
CA   Telomerase immortalized cell line
DT   Created: 16-12-21; Last updated: 10-04-25; Version: 7
//
RX   Patent=CN110904051B;
RA   Wu H., Wang Z.-Y., Xue L., Chen H.-S.;
RT   "Human auditory neuroma immortalized cell line, preparation method and
RT   application thereof.";
RL   Patent number CN110904051B, 06-Aug-2021.
//
RX   PubMed=34539995; PMCID=PMC8430072;
RA   Xue L., He W.-W., Wang Z.-G., Chen H.-S., Wang Z.-Y., Wu H.;
RT   "Characterization of a newly established schwannoma cell line from a
RT   sporadic vestibular schwannoma patient.";
RL   Am. J. Transl. Res. 13:8787-8803(2021).
//
RX   PubMed=35359340; DOI=10.1155/2022/7507857; PMCID=PMC8961447;
RA   He W.-W., Shu W.-Y., Xue L., Wang Y.-X., Chai Y.-C., Wu H.,
RA   Wang Z.-Y.;
RT   "Synergistic effect of erastin combined with nutlin-3 on vestibular
RT   schwannoma cells as p53 modulates erastin-induced ferroptosis
RT   response.";
RL   J. Oncol. 2022:7507857.1-7507857.18(2022).
//