ID   HeLa-ACE2-TMPRSS2
AC   CVCL_B3LV
DR   JCRB; JCRB1835
DR   Wikidata; Q110432868
RX   PubMed=22496216;
CC   Population: African American.
CC   Virology: Can be used to isolate human coronavirus NL63 (HCoV-NL63) (JCRB=JCRB1835).
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:13557; ACE2.
CC   Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11876; TMPRSS2.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
ST   Source(s): JCRB=JCRB1835
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 13.3,14.3
ST   D16S539: 9,10
ST   D5S818: 11,12
ST   D7S820: 8,12,13
ST   TH01: 7
ST   TPOX: 8,12
ST   vWA: 16,18,19
DI   NCIt; C27677; Human papillomavirus-related endocervical adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1276 ! HeLa 229
SX   Female
AG   30Y6M
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 14-08-25; Version: 11
//
RX   PubMed=22496216; DOI=10.1128/JVI.00094-12; PMCID=PMC3393535;
RA   Kawase, Miyuki
RA   Shirato, Kazuya
RA   van der Hoek, Lia
RA   Taguchi, Fumihiro
RA   Matsuyama, Shutoku
RT   "Simultaneous treatment of human bronchial epithelial cells with
RT   serine and cysteine protease inhibitors prevents severe acute
RT   respiratory syndrome coronavirus entry.";
RL   J. Virol. 86:6537-6545(2012).
//