ID   Akata EBER(-) EBV
AC   CVCL_B3LU
DR   cancercelllines; CVCL_B3LU
DR   JCRB; JCRB1832
DR   Wikidata; Q110432576
RX   PubMed=17686859;
CC   Population: Japanese.
CC   Virology: EBV-negative cell line re-infected with recombinant EBV whose genome is KO for EBER1 and EBER2.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leufs*57 (c.569delC); ClinVar=VCV000825904; Zygosity=Unspecified (from parent cell line).
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Cell type: B-cell; CL=CL_0000236.
ST   Source(s): JCRB=JCRB1832
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 8,12
ST   D16S539: 10,11
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   TH01: 9
ST   TPOX: 8,11
ST   vWA: 14,16
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_VN89 ! Akata-EBV-N
SX   Female
AG   4Y
CA   Cancer cell line
DT   Created: 16-12-21; Last updated: 14-08-25; Version: 10
CH   CVCL_B6R3 ! Akata delta1 EBER2(+)
CH   CVCL_B3MK ! Akata delta2 EBER1(+)
CH   CVCL_B3M6 ! Akata EBER(+) EBV
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RX   PubMed=17686859; DOI=10.1128/JVI.00579-07; PMCID=PMC2045559;
RA   Wu, Yi
RA   Maruo, Seiji
RA   Yajima, Misako
RA   Kanda, Teru
RA   Takada, Kenzo
RT   "Epstein-Barr virus (EBV)-encoded RNA 2 (EBER2) but not EBER1 plays a
RT   critical role in EBV-induced B-cell growth transformation.";
RL   J. Virol. 81:11236-11245(2007).
//