ID   ESKOL
AC   CVCL_B398
SY   Eskol
DR   Cosmic; 1809510
DR   Cosmic; 2690007
DR   GEO; GSM1374476
DR   Wikidata; Q54832831
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1895754;
RX   PubMed=11060441;
RX   PubMed=11755467;
RX   PubMed=22653958;
CC   Problematic cell line: Possibly misclassified. It is not certain that this cell line originate from a hairy cell leukemia (PubMed=22653958).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C7402; Hairy cell leukemia
DI   ORDO; Orphanet_58017; Classic hairy cell leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   69Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 15
CH   CVCL_W994 ! IREs-4
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RX   PubMed=22653958; DOI=10.1182/blood-2011-12-400374;
RA   Tiacci, Enrico
RA   Pucciarini, Alessandra
RA   Bigerna, Barbara
RA   Pettirossi, Valentina
RA   Strozzini, Francesca
RA   Martelli, Maria Paola
RA   Tabarrini, Alessia
RA   Drexler, Hans Gunther
RA   Falini, Brunangelo
RT   "Absence of BRAF-V600E in the human cell lines BONNA-12, ESKOL, HAIR-M,
RT   and HC-1 questions their origin from hairy cell leukemia.";
RL   Blood 119:5332-5333(2012).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
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RX   PubMed=11755467; DOI=10.1016/S0145-2126(01)00100-X;
RA   Khalaf, Waleed
RA   Maina, Caroline
RA   Byers, Joseph
RA   Harvey, William
RT   "Interferon-alpha 2b and vesnarinone influence levels of tumor
RT   necrosis factor-alpha, apoptosis, or interleukin 6 in ESKOL, a hairy
RT   cell leukemic cell line. A potential cytokine and oncogene
RT   relationship regulating apoptosis is suggested.";
RL   Leuk. Res. 26:169-177(2002).
//
RX   PubMed=1895754; DOI=10.1016/0145-2126(91)90077-7;
RA   Harvey, William
RA   Srour, Edward F.
RA   Turner, Rudolph
RA   Carey, Roger
RA   Maze, Rodney
RA   Starrett, Bradley
RA   Kanagala, Ravi
RA   Pereira, Daniel
RA   Merchant, Peggy
RA   Taylor, Milton W.
RA   Jansen, Jan
RT   "Characterization of a new cell line (ESKOL) resembling hairy-cell
RT   leukemia: a model for oncogene regulation and late B-cell
RT   differentiation.";
RL   Leuk. Res. 15:733-744(1991).
//
RX   PubMed=11060441; DOI=10.1159/000015656;
RA   Lindbjerg Andersen, Claus
RA   Ostergaard, Mette V.
RA   Nielsen, Bridget
RA   Pedersen, Bent
RA   Koch, Joachim
RT   "Characterization of three hairy cell leukemia- derived cell lines
RT   (ESKOL, JOK-1, and Hair-M) by multiplex-FISH, comparative genomic
RT   hybridization, FISH, PRINS, and dideoxyPRINS.";
RL   Cytogenet. Cell Genet. 90:30-39(2000).
//