ID   HUES 8
AC   CVCL_B207
SY   HUES-8; HUES8; HuES8; HuES08; HVRDe008-A
DR   EFO; EFO_0007093
DR   ENCODE; ENCBS458EUG
DR   ENCODE; ENCBS989VLH
DR   GEO; GSM608013
DR   GEO; GSM608030
DR   GEO; GSM621709
DR   GEO; GSM637761
DR   hPSCreg; HVRDe008-A
DR   NIHhESC; NIHhESC-10-0021
DR   SKIP; SKIP001912
DR   Wikidata; Q54896820
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=19200798;
RX   PubMed=21295703;
RX   PubMed=21637780;
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0021.
CC   Registration: Swiss research registry; BAG-hES-IMP-0056.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-018, Steering comm. appl. SCSC04-25(8).
CC   Doubling time: 48 hours (PubMed=14999088).
CC   Omics: Genomics; DNA methylation analysis.
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): PubMed=19200798; PubMed=21637780
ST   Amelogenin: X,Y
ST   CSF1PO: 10,12
ST   D13S317: 12,14
ST   D16S539: 9,12
ST   D18S51: 12,16
ST   D21S11: 28,29
ST   D3S1358: 15,19
ST   D5S818: 11
ST   D7S820: 11,12
ST   D8S1179: 13
ST   FGA: 20,25
ST   Penta D: 10,11
ST   Penta E: 7,10
ST   TH01: 7,9
ST   TPOX: 8,11
ST   vWA: 15,19
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 10-04-25; Version: 24
CH   CVCL_VR10 ! HUES8 iCas9
CH   CVCL_A8ZA ! HVRDe008-A-1
CH   CVCL_B5S4 ! HVRDe008-A-2
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi, Oluseun
RA   Aflatoonian, Behrouz
RA   Ahrlund-Richter, Lars
RA   Amit, Michal
RA   Andrews, Peter W.
RA   Beighton, Gemma
RA   Bello, Paul A.
RA   Benvenisty, Nissim
RA   Berry, Lorraine S.
RA   Bevan, Simon
RA   Blum, Barak
RA   Brooking, Justin
RA   Chen, Kevin G.
RA   Choo, Andre B.-H.
RA   Churchill, Gary A.
RA   Corbel, Marie
RA   Damjanov, Ivan
RA   Draper, Jonathan S.
RA   Dvorak, Petr
RA   Emanuelsson, Katarina
RA   Fleck, Roland A.
RA   Ford, Angela
RA   Gertow, Karin
RA   Gertsenstein, Marina
RA   Gokhale, Paul J.
RA   Hamilton, Rebecca S.
RA   Hampl, Ales
RA   Healy, Lyn E.
RA   Hovatta, Outi
RA   Hyllner, Johan
RA   Imreh, Marta P.
RA   Itskovitz-Eldor, Joseph
RA   Jackson, Jamie
RA   Johnson, Jacqueline L.
RA   Jones, Mark
RA   Kee, Kehkooi
RA   King, Benjamin L.
RA   Knowles, Barbara B.
RA   Lako, Majlinda
RA   Lebrin, Franck
RA   Mallon, Barbara S.
RA   Manning, Daisy
RA   Mayshar, Yoav
RA   McKay, Ronald Davies Graham
RA   Michalska, Anna E.
RA   Mikkola, Milla
RA   Mileikovsky, Maria
RA   Minger, Stephen Lewis
RA   Moore, Harry D.
RA   Mummery, Christine L.
RA   Nagy, Andras
RA   Nakatsuji, Norio
RA   O'Brien, Carmel M.
RA   Oh, Steve Kah-Weng
RA   Olsson, Cia
RA   Otonkoski, Timo
RA   Park, Kye-Yoon
RA   Passier, Robert
RA   Patel, Hema
RA   Patel, Minal J.
RA   Pedersen, Roger Arnold
RA   Pera, Martin F.
RA   Piekarczyk, Marian S.
RA   Reijo Pera, Renee A.
RA   Reubinoff, Benjamin E.
RA   Robins, Allan J.
RA   Rossant, Janet
RA   Rugg-Gunn, Peter
RA   Schulz, Thomas C.
RA   Semb, Henrik
RA   Sherrer, Eric S.
RA   Siemen, Henrike
RA   Stacey, Glyn N.
RA   Stojkovic, Miodrag
RA   Suemori, Hirofumi
RA   Szatkiewicz, Jin
RA   Turetsky, Tikva Tako
RA   Tuuri, Timo
RA   van den Brink, Stieneke
RA   Vintersten, Kristina
RA   Vuoristo, Sanna
RA   Ward-van Oostwaard, Dorien
RA   Weaver, Thomas A.
RA   Young, Lesley A.
RA   Zhang, Wei-Dong
RG   International Stem Cell Initiative;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001; PMCID=PMC3335201;
RA   Chen, Alice E.
RA   Egli, Dietrich Meinrad
RA   Niakan, Kathy K.
RA   Deng, Jie
RA   Akutsu, Hidenori
RA   Yamaki, Mariko
RA   Cowan, Chad A.
RA   Fitz-Gerald, Claire
RA   Zhang, Kun
RA   Melton, Douglas A.
RA   Eggan, Kevin Carl
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//
RX   PubMed=21295703; DOI=10.1016/j.cell.2010.12.032; PMCID=PMC3063454;
RA   Bock, Christoph
RA   Kiskinis, Evangelos
RA   Verstappen, Griet
RA   Gu, Hong-Cang
RA   Boulting, Gabriella L.
RA   Smith, Zachary D.
RA   Ziller, Michael Johannes
RA   Croft, Gist Fralley
RA   Amoroso, Mackenzie Weygandt
RA   Oakley, Derek H.
RA   Gnirke, Andreas
RA   Eggan, Kevin Carl
RA   Meissner, Alexander
RT   "Reference maps of human ES and iPS cell variation enable
RT   high-throughput characterization of pluripotent cell lines.";
RL   Cell 144:439-452(2011).
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan, Chad A.
RA   Klimanskaya, Irina V.
RA   McMahon, Jill
RA   Atienza, Jocelyn
RA   Witmyer, Jeannine
RA   Zucker, Jacob P.
RA   Wang, Shun-Ping
RA   Morton, Cynthia Casson
RA   McMahon, Andrew P.
RA   Powers, Doug
RA   Melton, Douglas A.
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=21637780; DOI=10.1371/journal.pgen.1002085; PMCID=PMC3102737;
RA   Nishino, Koichiro
RA   Toyoda, Masashi
RA   Yamazaki-Inoue, Mayu
RA   Fukawatase, Yoshihiro
RA   Chikazawa, Emi
RA   Sakaguchi, Hironari
RA   Akutsu, Hidenori
RA   Umezawa, Akihiro
RT   "DNA methylation dynamics in human induced pluripotent stem cells over
RT   time.";
RL   PLoS Genet. 7:e1002085.1-e1002085.14(2011).
//