ID   HUES 5
AC   CVCL_B183
SY   HUES-5; HUES5; HuES5; Hues5; HVRDe005-A
DR   hPSCreg; HVRDe005-A
DR   ISCR; 106
DR   NIHhESC; NIHhESC-10-0018
DR   SKIP; SKIP001483
DR   SKIP; SKIP001909
DR   Wikidata; Q54896787
RX   PubMed=14999088;
RX   PubMed=17287758;
RX   PubMed=17572666;
RX   PubMed=18772870;
RX   PubMed=19200798;
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0018.
CC   Registration: Swiss research registry; BAG-hES-IMP-0037.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-008, Steering comm. appl. SCSC04-25(5).
CC   Doubling time: 72 hours (PubMed=14999088).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): PubMed=19200798
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,13
ST   D16S539: 12,13
ST   D18S51: 13,16
ST   D21S11: 27,28
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 11,12
ST   D8S1179: 12,14
ST   FGA: 20
ST   Penta D: 10,12
ST   Penta E: 10,11
ST   TH01: 7,9
ST   TPOX: 11
ST   vWA: 15,17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 19
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17287758; DOI=10.1038/nbt1285;
RA   Baker D.E.C., Harrison N.J., Maltby E., Smith K., Moore H.D., Shaw P.J.,
RA   Heath P.R., Holden H., Andrews P.W.;
RT   "Adaptation to culture of human embryonic stem cells and oncogenesis
RT   in vivo.";
RL   Nat. Biotechnol. 25:207-215(2007).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=18772870; DOI=10.1038/nprot.2008.140;
RA   Braam S.R., Denning C., Matsa E., Young L.E., Passier R.,
RA   Mummery C.L.;
RT   "Feeder-free culture of human embryonic stem cells in conditioned
RT   medium for efficient genetic modification.";
RL   Nat. Protoc. 3:1435-1443(2008).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//