ID   HUES 15
AC   CVCL_B145
SY   HUES-15; HUES15; HuES15; HVRDe015-A
DR   hPSCreg; HVRDe015-A
DR   ISCR; 116
DR   NIHhESC; NIHhESC-10-0028
DR   SKIP; SKIP001498
DR   SKIP; SKIP001919
DR   Wikidata; Q54896744
RX   PubMed=14999088;
RX   PubMed=17572666;
RX   PubMed=18772870;
RX   PubMed=19200798;
CC   From: Harvard University; Boston; USA.
CC   Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0028.
CC   Registration: UK Stem Cell Bank (UKSCB); R-06-015, Steering comm. appl. SCSC04-25(15).
CC   Doubling time: 48 hours (PubMed=14999088).
CC   Donor information: Embryo is sibling to that giving rise to HUES 14 (Cellosaurus=CVCL_B144).
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
ST   Source(s): PubMed=19200798
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 9
ST   D16S539: 9,10
ST   D18S51: 13,15
ST   D21S11: 28,30
ST   D3S1358: 17,18
ST   D5S818: 11,12
ST   D7S820: 10
ST   D8S1179: 11,13
ST   FGA: 20,21
ST   Penta D: 10,12
ST   Penta E: 16,18
ST   TH01: 7
ST   TPOX: 8,11
ST   vWA: 16,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 20
//
RX   PubMed=14999088; DOI=10.1056/NEJMsr040330;
RA   Cowan C.A., Klimanskaya I.V., McMahon J., Atienza J., Witmyer J.,
RA   Zucker J.P., Wang S.-P., Morton C.C., McMahon A.P., Powers D.,
RA   Melton D.A.;
RT   "Derivation of embryonic stem-cell lines from human blastocysts.";
RL   N. Engl. J. Med. 350:1353-1356(2004).
//
RX   PubMed=17572666; DOI=10.1038/nbt1318;
RA   Adewumi O., Aflatoonian B., Ahrlund-Richter L., Amit M., Andrews P.W.,
RA   Beighton G., Bello P.A., Benvenisty N., Berry L.S., Bevan S., Blum B.,
RA   Brooking J., Chen K.G., Choo A.B.-H., Churchill G.A., Corbel M.,
RA   Damjanov I., Draper J.S., Dvorak P., Emanuelsson K., Fleck R.A.,
RA   Ford A., Gertow K., Gertsenstein M., Gokhale P.J., Hamilton R.S.,
RA   Hampl A., Healy L.E., Hovatta O., Hyllner J., Imreh M.P.,
RA   Itskovitz-Eldor J., Jackson J., Johnson J.L., Jones M., Kee K.,
RA   King B.L., Knowles B.B., Lako M., Lebrin F., Mallon B.S., Manning D.,
RA   Mayshar Y., McKay R.D.G., Michalska A.E., Mikkola M., Mileikovsky M.,
RA   Minger S.L., Moore H.D., Mummery C.L., Nagy A., Nakatsuji N.,
RA   O'Brien C.M., Oh S.K.-W., Olsson C., Otonkoski T., Park K.-Y.,
RA   Passier R., Patel H., Patel M.J., Pedersen R., Pera M.F.,
RA   Piekarczyk M.S., Reijo Pera R.A., Reubinoff B.E., Robins A.J.,
RA   Rossant J., Rugg-Gunn P., Schulz T.C., Semb H., Sherrer E.S., Siemen H.,
RA   Stacey G.N., Stojkovic M., Suemori H., Szatkiewicz J., Turetsky T.T.,
RA   Tuuri T., van den Brink S., Vintersten K., Vuoristo S.,
RA   Ward-van Oostwaard D., Weaver T.A., Young L.A., Zhang W.-D.;
RT   "Characterization of human embryonic stem cell lines by the
RT   International Stem Cell Initiative.";
RL   Nat. Biotechnol. 25:803-816(2007).
//
RX   PubMed=18772870; DOI=10.1038/nprot.2008.140;
RA   Braam S.R., Denning C., Matsa E., Young L.E., Passier R.,
RA   Mummery C.L.;
RT   "Feeder-free culture of human embryonic stem cells in conditioned
RT   medium for efficient genetic modification.";
RL   Nat. Protoc. 3:1435-1443(2008).
//
RX   PubMed=19200798; DOI=10.1016/j.stem.2008.12.001;
RA   Chen A.E., Egli D., Niakan K.K., Deng J., Akutsu H., Yamaki M.,
RA   Cowan C.A., Fitz-Gerald C., Zhang K., Melton D.A., Eggan K.C.;
RT   "Optimal timing of inner cell mass isolation increases the efficiency
RT   of human embryonic stem cell derivation and allows generation of
RT   sibling cell lines.";
RL   Cell Stem Cell 4:103-106(2009).
//